DALLAS, Sept. 30 /PRNewswire/ -- Determined to fast track research into help for breast cancer patients who can't wait, Susan G. Komen for the Cure(R) is distributing an unprecedented $100 million in grants to American and international scientists this year alone, the organization announced in unveiling its 2008 grants portfolio today.
(Logo: http://www.newscom.com/cgi-bin/prnh/20070122/NYM084LOGO)
It is the largest commitment of breast cancer research funding by a single nonprofit organization, targeted to 81 universities and hospitals in 27 states and five countries. These grants represent research with the highest likelihood of producing results for patients during the next decade.
"There's a tremendous urgency to translate what we're learning in the lab into treatments for patients, particularly patients with very aggressive cancers who don't have years to wait," said Dr. Eric P. Winer, chief scientific advisor to Susan G. Komen for the Cure and director of the Breast Oncology Center at Dana-Farber Cancer Institute.
"The grants we are funding focus on safely and effectively bringing treatments to cancer patients in a more timely way than we have been able to in the past," Winer added.
"We've revamped Komen's research program, challenging the best minds to solve the most difficult issues in breast cancer," said Hala Moddelmog, president and CEO of Susan G. Komen for the Cure. "These grants are geared to results -- finding cures, tailoring treatments and resolving the issues that have stymied the search for a breast cancer cure."
Some of the biggest questions to be tackled by the Komen-funded research include:
-- Why do some breast cancers respond to certain treatments, and others
don't?
-- How can we prevent the spread of breast cancer to other organs?
-- Does diet and/or obesity play a role in cancer development and
treatment?
-- Can we predict who is most at risk for developing breast cancer?
-- Can we develop a cancer vaccine?
-- What technologies will help detect breast cancer at its earliest
possible stage?
-- What treatments can prolong the lives of those women living with
advanced breast cancer?
During the past 25 years, Komen for the Cure has raised and distributed $1.2 billion for research and community health programs. And Komen is pledging to invest another $2 billion during the next 10 years.
This year, Komen introduces new research programs called Promise Grants, which are worth millions of dollars and last for five years. They are designed to get scientists and doctors to work together in new ways to bring treatments out of the laboratory to patients as quickly as possible. Komen also is funding new and bigger grants to attract and retain young cancer researchers.
Moddelmog noted that research and awareness funding has helped ease suffering from breast cancer. "In the past 20 years, we've gone from a time when breast cancer was not even discussed, to a new era with higher survivor rates and less invasive treatments than existed even just a decade ago," Moddelmog said.
"Even so, we have so much more to do. Almost 200,000 women will be diagnosed with breast cancer in the U.S. this year and more than 40,000 women and men will die of this disease. That adds urgency to our mission to end breast cancer forever."
The Komen grants undergo a rigorous peer-review process by groups of laboratory scientists, clinicians and advocates. These grants fall into the following categories:
* Promise Grants: Large-scale grants, up to $7.5 million each during a five-year period, targeted to research that brings science to the bedside quicker than ever before. Komen will provide $35 million in Promise grants to seven, multi-year projects in 2008.
* Post-Doctoral Research: Grants of $60,000 per year to attract and retain promising young researchers nationwide and internationally. Forty-six scientists will share grant funding that totals $7.7 million over three years.
* Career Catalyst Research: Grants of $150,000 per year for three years to fill a critical gap in support and stimulate the transition from training to independence among promising cancer investigators. Total funding: $10.9 million to 26 researchers.
* Investigator Initiated Research: Grants of up to $200,000 per year for three years to explore new ideas and approaches leading to reductions in breast cancer mortality and/or the incidence within the decade. Total funding: $35.3 million for 60 grants.
* Affiliate Grants: Special grants co-funded by 15 Komen Affiliates to institutions in their hometowns or states.
In addition, Komen has directed $13 million to other cancer research organizations to fund collaborative projects. A complete list of the grants can be found on www.komen.org/grants
About Susan G. Komen for the Cure(R)
Nancy G. Brinker promised her dying sister, Susan G. Komen, she would do everything in her power to end breast cancer forever. In 1982, that promise became Susan G. Komen for the Cure and launched the global breast cancer movement. Today, Komen for the Cure is the world's largest grassroots network of breast cancer survivors and activists fighting to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Komen Race for the Cure Series, we have invested more than $1.2 billion to fulfill our promise, becoming the largest source of nonprofit funds dedicated to the fight against breast cancer in the world. For more information about Susan G. Komen for the Cure, breast health or breast cancer, visit http://www.komen.org or call 1-877 GO KOMEN.
The following research and training grants being funded by Susan G. Komen for the Cure in 2008 address the biggest questions in breast cancer research, allowing us to begin to prevent breast cancer development, find cancers when they are most easily cured, and to bring more effective treatments to patients.
Research topic areas are noted for each grant, and descriptions of the focus and promise of research in these topic areas are described in the Research Topic Descriptions document available on http://www.komen.org. A pound sign (#) designates projects that are being co-funded by the local Komen Affiliate. And asterisk (*) indicates that contract negotiations have not been finalized.
Total
Total Amount Institution Total State Principal
State Institution Awarded Dollars Dollars Investigator
Australia University of Mark Smyth,
Melbourne $598,492 Ph.D.*
Australia University of Erik Thompson,
Melbourne $180,000 $778,492 $778,492 Ph.D.
Belgium Katholieke Peter
Universiteit Carmeliet,
Leuven-Vib $576,000 $576,000 $576,000 M.D., Ph.D.*
Canada Samuel
Lunenfeld
Research
Institute at
Mount Sinai
Hospital,
University of Pamela
Toronto $495,374 $495,374 Goodwin, M.D.*
Canada Sir Mortimer B.
Davis - Jewish
General
Hospital, Lady
Davis
Institute for Marc
Medical Tischkowitz,
Research $290,852 $290,852 M.D., Ph.D.
Canada The Hospital
for Sick Sean Egan,
Children $595,274 $595,274 $1,381,500 Ph.D.*
Giuseppe
Italy European Viale, M.D.*
Institute of Olivia Pagani,
Oncology $3,929,682 $3,929,682 $3,929,682 MD
Ecole
Polytechnique
Federale de Melody Swartz,
Switzerland Lausanne $150,000 $150,000 $150,000 Ph.D.
AL University of
Alabama at Elizabeth
Birmingham $120,000 $120,000 $120,000 Sztul, Ph.D.*
CA California
Pacific John Muschler,
Medical Center $180,000 $180,000 Ph.D.*
CA City of Hope
Beckman
Research Shiuan Chen,
Institute $600,000 $600,000 Ph.D.
CA Lawrence
Berkeley
National Mina Bissell,
Laboratory $118,322 $118,322 Ph.D.*
CA Stanford
University,
School of David Feldman,
Medicine $599,999 M.D.
CA Stanford
University,
School of Robert
Medicine $180,000 Carlson, M.D.
CA Stanford
University,
School of James Ford,
Medicine $180,000 Ph.D.
CA Stanford
University,
School of James Ford,
Medicine $180,000 $1,139,999 Ph.D.
CA University of
California at Randall
San Diego $600,000 Johnson, Ph.D.
CA University of Marilyn
California at Farquhar,
San Diego $180,000 Ph.D.
CA University of Michael
California at Rosenfeld,
San Diego $180,000 M.D.
CA University of
California at Michael Karin,
San Diego $180,000 $1,140,000 Ph.D.
CA University of
California at Elad Ziv,
San Francisco $596,228 M.D.*
CA University of
California at Gerard Evan,
San Francisco $600,000 Ph.D.*
CA University of
California at Andrei Goga,
San Francisco $600,000 M.D., Ph.D.*
CA University of
California at Zena Werb,
San Francisco $180,000 DVM, Ph.D.*
CA University of
California at Mark Moasser,
San Francisco $180,000 Ph.D.*
Mark Moasser,
CA University of M.D.*
California at James Wells,
San Francisco $1,000,000 $3,156,228 PhD
CA University of
Southern Peter Laird,
California $180,000 Ph.D.*
CA University of
Southern
California
(USC), Keck
School of Michael Kahn,
Medicine $600,000 $780,000 $7,114,549 Ph.D.
CO University of
Colorado
Health Steven
Sciences Anderson,
Center $599,999 $599,999 $599,999 Ph.D.*
Nita Maihle,
CT Yale University $180,000 Ph.D.*
CT Yale
University, Joshua
School of VanHouten,
Medicine $450,000 Ph.D.*
CT Yale
University,
School of Patrick Sung,
Medicine $180,000 $810,000 $810,000 Ph.D.
DC Georgetown
University,
Lombardi
Comprehensive Priscilla
Cancer Center $180,000 $180,000 $180,000 Furth, M.D.
FL H. Lee Moffitt
Cancer Center
& Research Geza Acs,
Institute $595,811 $595,811 M.D., Ph.D.
FL University of Brian Law,
Florida $600,000 $600,000 $1,195,811 Ph.D.#
IA University of
Iowa at Carver Frederick
College of Domann,
Medicine $180,000 $180,000 $180,000 Ph.D.*#
IL Evanston
Northwestern
Healthcare
Research Toru Ouchi,
Institute $600,000 $600,000 Ph.D.
IL Loyola
University, Kimberly
Chicago $586,581 $586,581 Foreman, Ph.D.
IL Northwestern
University,
Feinberg
School of Ming Zhang,
Medicine $600,000 $600,000 Ph.D.
IL Southern
Illinois
University
School of Kounosuke
Medicine $177,975 $177,975 Watabe, Ph.D.
IL University of
Illinois at Rohit
Champaign and Bhargava,
Urbana $600,000 $600,000 $2,564,556 Ph.D.
IN Indiana
University,
School of Hiromi Tanaka,
Medicine $450,000 Ph.D.*
IN Indiana
University,
School of David Gilley,
Medicine $600,000 Ph.D.
IN Indiana
University,
School of John Foley,
Medicine $463,499 $1,513,499 $1,513,499 Ph.D.*#
KY University of Robert Stout,
Louisville $600,000 Ph.D.
KY University of
Louisville at
School of Carolyn
Medicine $600,000 $1,200,000 $1,200,000 Klinge, Ph.D.#
MA Boston
University Sam
School of Thiagalingam,
Medicine $600,000 $600,000 Ph.D.
MA Brigham and Stephen
Women's Elledge,
Hospital $180,000 $180,000 Ph.D.*
MA Dana-Farber
Cancer Xiuwei Yang,
Institute $448,371 Ph.D.
MA Dana-Farber Piotr
Cancer Sicinski,
Institute $600,000 M.D., Ph.D.*
MA Dana-Farber Kornelia
Cancer Polyak, M.D.,
Institute $180,000 Ph.D.
MA Dana-Farber
Cancer Myles Brown,
Institute $120,000 Ph.D.
MA Dana-Farber Geoffrey
Cancer Shapiro, M.D.,
Institute $120,000 $1,468,371 Ph.D.*
Marielle
MA Massachusetts Scherrer-
General Crosbie, M.D.,
Hospital $600,000 $600,000 Ph.D.
MA Tufts
University $180,000 $180,000 Amy Yee, Ph.D.
MA Whitehead
Institute for
Biomedical Harvey Lodish,
Research $180,000 $180,000 $3,208,371 Ph.D.
MD Johns Hopkins Rachel
University $599,798 Karchin, Ph.D.
MD Johns Hopkins Robert Casero,
University $600,000 Ph.D.
MD Johns Hopkins
University,
Kimmel Cancer Nita Ahuja,
Center $573,030 M.D.*
MD Johns Hopkins
University,
Kimmel Cancer Vered Stearns,
Center $120,000 M.D.*#
MD Johns Hopkins
University, Edward
School of Gabrielson,
Medicine $600,000 Ph.D.*
MD Johns Hopkins
University, Giovanni
School of Parmigiani,
Medicine $573,750 Ph.D.
MD Johns Hopkins
University,
School of Cynthia
Medicine $180,000 $3,246,578 Zahnow, Ph.D.
MD University of
Maryland at Jeffrey
Baltimore $600,000 Winkles, Ph.D.
MD University of
Maryland at
School of Geoffrey
Medicine $450,001 $1,050,001 $4,296,579 Girnun, Ph.D.
MI Wayne State
University,
Karmanos
Cancer Guojun Wu,
Institute $450,000 Ph.D.#
MI Wayne State
University,
Karmanos
Cancer Julie Boerner,
Institute $450,000 $900,000 $900,000 Ph.D.#
MN Mayo Clinic and
Foundation, Fergus Couch,
Rochester $600,000 Ph.D.*
MN Mayo Clinic and
Foundation, Fergus Couch,
Rochester $180,000 $780,000 Ph.D.
MN University of Michael
Minnesota at Grossmann,
Twin Cities $448,884 Ph.D.
MN University of Kathryn
Minnesota at Schwertfeger,
Twin Cities $450,000 $898,884 $1,678,884 Ph.D.
MO University of
Missouri at Edward Sauter,
Columbia $600,090 $600,090 M.D., Ph.D.*
MO Washington
University at
St. Louis,
School of Simon Powell,
Medicine $600,000 M.D., Ph.D.*
MO Washington
University at
St. Louis,
School of Helen Piwnica-
Medicine $600,000 Worms, Ph.D.
MO Washington
University at
St. Louis,
School of Loren Michel,
Medicine $600,000 M.D.
MO Washington
University in Rebecca Aft,
St. Louis $600,000 M.D., Ph.D.
MO Washington William
University in Gillanders,
St. Louis $180,000 $2,580,000 $3,180,090 M.D.
NC Duke University Michael Morse,
Medical Center $512,984 M.D.*
NC Duke University
Medical Center $600,000 Jun Zhu, Ph.D.
NC Duke University Wei Chen,
Medical Center $600,000 Ph.D.
NC Duke University H. Kim Lyerly,
Medical Center $180,000 Ph.D.
NC Duke
University,
School of Gerard Blobe,
Medicine $180,000 $2,072,984 Ph.D.
NC University of Rebecca
North Carolina Cleveland,
at Chapel Hill $341,156 Ph.D.
NC University of
North Carolina Yue Xiong,
at Chapel Hill $600,000 Ph.D.
NC University of
North Carolina Kathleen
at Chapel Hill $599,997 Dorsey, Ph.D.
NC University of
North Carolina Channing Der,
at Chapel Hill $180,000 $1,721,153 Ph.D.#
NC Wake Forest
University
Health Kazushi Inoue,
Sciences $180,000 $180,000 $3,974,137 M.D., Ph.D.
NE University of Surinder
Nebraska $180,000 Batra, Ph.D.
NE University of
Nebraska James Shull,
Medical Center $599,996 $779,996 $779,996 Ph.D.
NJ University of
Medicine &
Dentistry of
New Jersey,
Robert Wood
Johnson Ling Qin,
Medical School $450,000 $450,000 $450,000 Ph.D.#
NY Albany Medical Jihe Zhao,
College $180,000 $180,000 M.D.,Ph.D.
NY Albert Einstein
College of
Medicine at
Yeshiva Nancy
University $180,000 $180,000 Carrasco, M.D.
NY Cornell
University, Richard
Ithaca $600,000 Cerione, Ph.D.
NY Cornell
University,
Weill Medical David Lyden,
College $600,000 $1,200,000 M.D., Ph.D.
Joseph
NY New York Guttenplan,
University $600,000 $600,000 Ph.D.
NY Polytechnic
Institute , Stavroula
Brooklyn, NY $450,000 $450,000 Sofou, Ph.D.#
NY Riverside
Research Sheikh Alam,
Institute $594,000 $594,000 Ph.D.
NY State
University of
New York at Emily Chen,
Stony Brook $300,000 Ph.D.
NY State
University of
New York at Wei-Xing Zong,
Stony Brook $450,000 $750,000 Ph.D.
NY University of
Rochester Sabine
School of Brouxhon,
Medicine $299,872 $299,872 $4,253,872 M.D.#
OH Cleveland
Clinic Li-Xin Wang,
Foundation $449,447 $449,447 M.D., Ph.D.#
OH Ohio State
University,
College of Huey-Jen Lin,
Medicine $450,000 $450,000 Ph.D.*
OH University of Shao-Chun
Cincinnati $600,000 $600,000 $1,499,447 Wang, Ph.D.*#
OK University of
Oklahoma
Health
Sciences Wei-Qun Ding,
Center $597,500 $597,500 $597,500 Ph.D.
PA Fox Chase Andrew Godwin,
Cancer Center $180,000 $180,000 Ph.D.
PA Pennsylvania
State
University
College of David Feith,
Medicine $600,000 Ph.D.
PA Pennsylvania
State Andrea Manni,
University M.D.
College of Karam El-
Medicine $7,498,495 $8,098,495 Bayoumy, Ph.D.
PA Thomas
Jefferson Philippe
University $450,000 Frank, Ph.D.
PA Thomas
Jefferson Jean-Francois
University $450,001 Jasmin, Ph.D.
PA Thomas Agnieszka
Jefferson Witkiewicz,
University $450,000 M.D.
PA Thomas
Jefferson Hallgeir Rui,
University $180,000 $1,530,001 M.D., Ph.D.
PA University of
Pennsylvania
School of
Medicine $448,837 Lin Li, Ph.D.
PA University of
Pennsylvania Andrew
School of Maidment,
Medicine $120,000 $568,837 Ph.D.
PA University of Margarita
Pittsburgh $588,018 $588,018 $10,965,351 Zuley, M.D.
RI Brown Susan Gerbi,
University $600,000 $600,000 $600,000 Ph.D.*
SC Clemson Ya-Ping Sun,
University $180,000 $180,000 $180,000 Ph.D.*#
TN Vanderbilt
University David Cortez,
Medical Center $600,000 $600,000 $600,000 Ph.D.
TX Baylor College Debananda
of Medicine $180,000 Pati, Ph.D.
Powel Brown,
M.D., Ph.D.*
TX Baylor College Gordon Mills,
of Medicine $7,138,690 $7,318,690 M.D., Ph.D.
TX M.D. Anderson
Cancer Center, Christine
University of Stellrecht,
Texas $450,000 Ph.D.
TX M.D. Anderson
Cancer Center, Bulent
University of Ozpolat, M.D.,
Texas $406,579 Ph.D.
TX M.D. Anderson
Cancer Center,
University of Kapil Mehta,
Texas $582,064 Ph.D.
TX M.D. Anderson
Cancer Center,
University of Gordon Mills,
Texas $600,000 M.D., Ph.D.
TX M.D. Anderson
Cancer Center,
University of Yun Wu, M.D.,
Texas $600,000 Ph.D.
TX M.D. Anderson
Cancer Center, Laszlo
University of Radvanyi,
Texas $180,000 Ph.D.
TX M.D. Anderson
Cancer Center,
University of Shiaw-Yih Lin,
Texas $120,000 Ph.D.
TX M.D. Anderson
Cancer Center,
University of Kelly Hunt,
Texas $180,000 Ph.D.
Sai-ching
TX M.D. Anderson Yeung, M.D.,
Cancer Center, Ph.D.*
University of Mong-Hong Lee,
Texas $7,234,072 Ph.D.
Fredika
Robertson,
TX M.D. Anderson Ph.D.
Cancer Center, Massimo
University of Cristofanilli,
Texas $7,500,000 M.D.
TX M.D. Anderson William
Cancer Center, Symmans, M.D.*
University of Lajos Pusztai,
Texas $998,688 $18,851,403 M.D., Ph.D.
TX University of
North Texas at
Health Science Fang Fang
Center, Fort Zhang, M.D.,
Worth $243,202 $243,202 Ph.D.
TX University of
Texas at
Health Science Charles
Center at Streckfus,
Houston $429,634 DDS*
TX University of
Texas at
Health Science
Center at Mikhail
Houston $180,000 $609,634 Kolonin, Ph.D.
TX University of
Texas at
Medical
Branch, Binhua Zhou,
Galveston $600,000 $600,000 $27,622,929 M.D., Ph.D.
UT University of
Utah at
Huntsman
Cancer Alana Welm,
Institute $450,000 Ph.D.
UT University of
Utah at
Huntsman
Cancer Richard
Institute $528,629 $978,629 $978,629 Kerber, Ph.D.
VA University of
Virginia at
School of Sarah Aiyar,
Medicine $449,997 Ph.D.*
VA University of
Virginia at
School of Theresa Guise,
Medicine $120,000 $569,997 $569,997 Ph.D.*
WA University of
Washington at Mary Claire
Seattle $600,000 $600,000 $600,000 King, Ph.D.
Website: http://www.komen.org//