Pfizer Achieves Key 2006 Financial Targets

- Full-Year 2006 Revenues Grew 2 Percent to $48.4 Billion, Key Products Substantially Attained Targets, Nine Exceeded $1 Billion in Sales

Pfizer Achieves Key 2006 Financial Targets

NEW YORK, Jan. 22 /PRNewswire-FirstCall/ -- Pfizer Inc today announced that revenues for full-year 2006 increased 2 percent, reported diluted EPS grew 144 percent, and adjusted diluted EPS(1) grew 6 percent versus 2005. Revenues in the fourth quarter of 2006 were substantially unchanged, reported diluted EPS grew 257 percent, and adjusted diluted EPS(1) decreased 12 percent versus the comparable quarter in 2005.

"In the face of many challenges in 2006, we substantially achieved a number of financial targets that we set early in the year," said Pfizer Chairman and Chief Executive Officer Jeffrey B. Kindler. "We took decisive action and delivered solid performance despite challenges, including the significant revenue impact due to the loss of exclusivity of Zithromax and Zoloft in the U.S. We achieved revenue growth of 2 percent for the year. We delivered adjusted diluted EPS(1) of $2.06, in line with our upwardly revised guidance.

"While we attained nearly all of our financial targets for the year, we continue to face a difficult operating environment, including competitive challenges and the risks inherent in drug development. Our decision to discontinue development of torcetrapib/atorvastatin in early December 2006 was disappointing and brought into sharper focus the need to transform Pfizer over time to succeed in a dynamic healthcare marketplace. We are reviewing every aspect of our business, and I look forward to discussing our priorities when we meet with analysts in New York later today," Mr. Kindler concluded.

"During the fourth quarter of 2006, we strengthened our commitment to enhancing total return to shareholders," said Vice Chairman David Shedlarz. "We completed the divestiture of the Consumer Healthcare business in the quarter, receiving approximately $16.6 billion in proceeds. Combined with projected strong cash flow from operations over the next several years, these proceeds will be used to make key investments in new products and technologies and to support a strong dividend and an active share purchase program.

"In December 2006, Pfizer announced a 21-percent increase in its first- quarter 2007 dividend to 29 cents per share. This significant increase builds on a 26-percent dividend increase in 2006. Pfizer has now increased its dividend every year for 40 consecutive years, and in the past 10 years the company's dividend has increased on average 18 percent per year. The company also continued its substantial share purchase program by buying $2.5 billion of its common stock in the fourth quarter of 2006. Pfizer purchased $7.0 billion of common stock during 2006. During the past five years, Pfizer has purchased more than $35 billion of its common stock."

      Pfizer's Pharmaceutical Operations Substantially Meet Targets
                         for Key In-Line Products

"Worldwide pharmaceutical 2006 revenues met our expectations," said Ian Read, President of Worldwide Pharmaceutical Operations. "We focused on the top-line growth of key in-line medicines, including Lipitor, Celebrex, Lyrica, and Geodon, and we launched Sutent, Eraxis, Chantix, and Exubera in the U.S."

Worldwide pharmaceutical revenues were $45.1 billion for full-year 2006, a 2-percent increase compared to full-year 2005. In the U.S., revenues increased 4 percent for the full-year 2006 compared to the same period in 2005. A strong performance in the U.S. was driven by growth from several of our core products, including Lipitor (up 6 percent), Celebrex (up 24 percent), Geodon (up 31 percent), Norvasc (up 13 percent), Xalatan (up 12 percent), Zyrtec (up 15 percent), Detrol (up 14 percent), Zyvox (up 20 percent), Vfend (up 27 percent), Aromasin (up 34 percent), and Caduet (up 95 percent), as well as the successful launches of several new medicines.

Worldwide pharmaceutical operations substantially met the sales targets established at the beginning of the year for several key brands. Notwithstanding our original sales target of more than $13 billion for Lipitor, actual sales totaled $12.886 billion, representing 6-percent growth -- a substantial accomplishment in the face of intense branded and generic competition in the statin market. For Celebrex, sales of $2.039 billion exceeded our original goal of achieving sales of more than $2 billion, demonstrating that we are on our way to rebuilding physician and patient confidence in this important medicine. Worldwide sales of $1.156 billion for Lyrica significantly exceeded both the initial target of more than $900 million and the subsequent, raised target of more than $1 billion, a performance that establishes Lyrica as one of the most successful pharmaceutical market entries in recent years. Geodon reached $758 million in worldwide revenues, just short of our target of about $800 million. Nine Pfizer products surpassed $1 billion in sales in 2006, with Detrol and Lyrica joining this list for the first time.

Pharmaceutical revenues for the fourth quarter of 2006 were $11.7 billion worldwide, comparable to those in the fourth quarter of 2005, and were $6.1 billion in the U.S., down 3 percent, mainly reflecting the loss of exclusivity of Zoloft in the U.S. in June 2006. Worldwide sales of Celebrex, Geodon, and Lyrica in the fourth quarter of 2006 grew 15 percent, 32 percent, and 131 percent, respectively.

New Products Continue to Gain Momentum

2006 was an exciting year of product launches. Against an original target of six new-product entries in the U.S., we launched four products -- Eraxis, Sutent, Exubera, and Chantix. In Europe, Sutent and Exubera entered the marketplace, and Champix (the trade name for Chantix in Europe) was launched beginning in December 2006. Several key medicines received approval for new indications in 2006, including approvals of Lyrica for central neuropathic pain and generalized anxiety disorder in the EU, and Celebrex for juvenile rheumatoid arthritis in the U.S.

Progress Achieved in New-Product Pipeline

"We continued to advance the candidates in our pipeline during the fourth quarter of 2006," said Dr. John LaMattina, President, Pfizer Global Research and Development. Maraviroc, our CCR5 receptor antagonist to treat HIV infection, was submitted for approval in the U.S. and EU in December 2006. Maraviroc has been accepted for filing and granted an accelerated review in the EU.

A supplemental NDA filing for Lyrica in the treatment of fibromyalgia was submitted to the FDA on December 20, 2006. Fibromyalgia is characterized by chronic, widespread pain that affects tens of millions of people worldwide, predominantly women. It is frequently accompanied by disturbed sleep, anxious mood, and poor quality of life. Pfizer is excited about Lyrica as a potential breakthrough for patients for treatment in this area and expects approval and launch of this new indication in the U.S. in the second half of 2007.

  Four new programs advanced into Phase 3 during the quarter:

  -- Axitinib, our next-generation anti-angiogenesis agent to treat thyroid
     cancer,
  -- CP-945,598, our cannabinoid-1 antagonist to treat obesity and its
     devastating complications,
  -- Sutent for the treatment of metastatic breast cancer, and
  -- Zithromax/chloroquine to treat malaria, the single greatest killer of
     children in Africa.

Pfizer recently provided more detail on its pipeline than ever before with the launch of an on-line site for tracking development compounds across Pfizer's largest-ever pipeline. This new website, launched last month, will be updated twice a year and is available at http://www.pfizer.com/pipeline.

Pfizer Achieves Full-Year 2006 Financial Goals

In reviewing full-year 2006 results, Alan Levin, chief financial officer, said, "Pfizer delivered adjusted diluted EPS(1) of $2.06 for the full year, in line with our most recent guidance and representing growth of 6 percent compared to full-year 2005 adjusted diluted EPS(1) of $1.95. Adjusted diluted EPS(1) was well ahead of our original 2006 guidance of about $1.93 (restated to reflect the sale of our Consumer Healthcare business) due in part to greater savings associated with our broad-based Adapting to Scale (AtS) productivity program (savings of approximately $2.6 billion for the full year versus our original goal of about $2 billion), a lower effective tax rate, and fewer shares outstanding given increased share purchases. Reported diluted EPS of $2.66 included a one-time gain of $1.08 ($7.9 billion) associated with the recently completed divestiture of Pfizer Consumer Healthcare (PCH), among other factors.

"For the fourth quarter of 2006, adjusted diluted EPS(1) of $.43 declined by 12 percent relative to the comparable period in 2005, reflecting the timing of certain operating expenses in 2006. The cost of sales pre-tax component of adjusted income(1) in the quarter increased by 11 percent, reflecting the timing of implementation of inventory management initiatives, the impact of foreign exchange, and charges related to certain asset writedowns. The R&D pre-tax component of adjusted income(1) in the quarter grew by 22 percent, reflecting timing considerations associated with the advancement of development programs for pipeline products, expenditures associated with in- licensing of a new compound, and the establishment of various research collaborations with third parties, among other factors. Reported net income of $9.4 billion for the fourth quarter included a gain of $7.9 billion on the sale of our Consumer Healthcare business, as well as purchase-accounting- related charges, costs associated with our expanded AtS productivity initiative, and a $320 million charge related to the impairment of intangible assets associated with Depo-Provera, a contraceptive product.

"We will discuss our forward-looking financial guidance during this afternoon's analyst meeting," Mr. Levin concluded.

For additional details, please see the attached financial schedules, product revenue tables, supplemental financial information, and Disclosure Notice.

  (1) "Adjusted income" and "adjusted diluted earnings per share (EPS)" are
      defined as reported net income and reported diluted EPS excluding
      purchase-accounting adjustments, acquisition-related costs,
      discontinued operations, cumulative effect of a change in accounting
      principles, and certain significant items.  As described under
      Adjusted Income in the Management's Discussion and Analysis of
      Financial Condition and Results of Operations section of Pfizer's Form
      10-Q for the quarterly period ended October 1, 2006, management uses
      adjusted income, among other factors, to set performance goals and to
      measure the performance of the overall company.  We believe that
      investors' understanding of our performance is enhanced by disclosing
      this measure.  Reconciliations of fourth-quarter and full-year 2006
      and 2005 adjusted income and adjusted diluted EPS to reported net
      income and reported diluted EPS, as well as a reconciliation of the
      original $1.93 estimate of full-year 2006 adjusted diluted EPS to
      reported diluted EPS, are provided in the materials accompanying this
      report.  The adjusted income and adjusted diluted EPS measures are
      not, and should not be viewed as, substitutes for U.S. GAAP net income
      and diluted EPS.



                     PFIZER INC AND SUBSIDIARY COMPANIES
                      CONSOLIDATED STATEMENTS OF INCOME
                                 (UNAUDITED)

  (millions of dollars, except per common share data)

                         Fourth Quarter   % Incr./      Full Year   % Incr./
                         2006      2005    (Decr.)   2006      2005  (Decr.)

   Revenues            $12,603    $12,547     -    $48,371   $47,405     2
   Costs and expenses:
    Cost of sales(a)     2,217      1,982    12      7,640     7,232     6
    Selling,
     informational and
     administrative
     expenses(a)         4,562      4,356     5     15,589    15,313     2
    Research and
     development
     expenses(a)         2,412      1,970    22      7,599     7,256     5
    Amortization of
     intangible assets     815        830    (2)     3,261     3,399    (4)
    Acquisition-related
     in-process
     research and
     development
     charges               322          -     *        835     1,652   (49)
    Restructuring
     charges and
     acquisition-
     related costs         507        573   (12)     1,323     1,356    (2)
    Other
     (income)/deductions
     -- net                 54       (306)    *       (904)      397     *
   Income from
    continuing
    operations before
    provision for
    taxes on income,
    minority interests
    and cumulative
    effect of a
    change in
    accounting
    principles           1,714      3,142   (45)    13,028    10,800    21
   Provision for taxes
    on income              223        536   (58)     1,992     3,178   (37)
   Minority interests        2          6   (65)        12        12     4
   Income from
    continuing
    operations before
    cumulative
    effect of a change
    in accounting
    principles           1,489      2,600   (43)    11,024     7,610    45
   Discontinued
    operations:
    Income from
     discontinued
     operations -- net
     of tax                103        152   (32)       433       451    (4)
    Gains on sales of
     discontinued
     operations -- net
     of tax              7,857          3    M+      7,880        47    M+
   Discontinued
    operations -- net
    of tax               7,960        155    M+      8,313       498    M+
   Income before
    cumulative effect
    of a change in
    accounting
    principles           9,449      2,755   243     19,337     8,108   138
   Cumulative effect of
    a change in
    accounting
    principles -- net
    of tax                   -        (23)    *          -       (23)    *
   Net income           $9,449     $2,732   246    $19,337    $8,085   139
   Earnings per common
    share - Basic:
    Income from
     continuing
     operations before
     cumulative
     effect of a change
     in accounting
     principles          $0.21      $0.35   (40)     $1.52     $1.03    48
    Discontinued
     operations -- net
     of tax               1.11       0.02    M+       1.15      0.07    M+
    Income before
     cumulative effect
     of a change in
     accounting
     principles           1.32       0.37   257       2.67      1.10   143
    Cumulative effect
     of a change in
     accounting
     principles              -          -     -          -         -     -
    Net income           $1.32      $0.37   257      $2.67     $1.10   143
   Earnings per common
    share - Diluted:
    Income from
     continuing
     operations before
     cumulative
     effect of a change
     in accounting
     principles          $0.21      $0.35   (40)     $1.52     $1.02    49
    Discontinued
     operations -- net
     of tax               1.11       0.02    M+       1.14      0.07    M+
    Income before
     cumulative effect
     of a change in
     accounting
     principles           1.32       0.37   257       2.66      1.09   144
    Cumulative effect
     of a change in
     accounting
     principles              -          -     -          -         -     -
    Net income           $1.32      $0.37   257      $2.66     $1.09   144
   Weighted-average
    shares used to
    calculate earnings
    per common share:
    Basic                7,144      7,327            7,242     7,361
    Diluted              7,171      7,368            7,274     7,411


  (a) Exclusive of amortization of intangible assets, except as discussed in
      footnote 4 below.

   *  Calculation not meaningful.

   M+ Change greater than one-thousand percent.
   Certain amounts and percentages may reflect rounding adjustments.

  1.  The above financial statement presents the three-month and twelve-
      month periods ended December 31 of each year.  Subsidiaries operating
      outside the United States are included for the three-month and twelve-
      month periods ended November 30 of each year.
  2.  In December 2006, we sold our Consumer Healthcare business for
      approximately $16.6 billion.  The above financial statement reflects
      this business as discontinued operations for all periods through
      December 20, 2006, including our international subsidiaries.
  3.  As required, the estimated value of Acquisition-related in-process
      research and development charges(IPR&D) is expensed at acquisition
      date. In 2006, we expensed $835 million of IPR&D, of which $322
      million related to our acquisition of PowderMed Ltd. in the fourth
      quarter and $513 million primarily related to our acquisition of Rinat
      Neurosciences Corp. in the second quarter. In 2005, we expensed $1.7
      billion of IPR&D, of which $1.4 billion related to our acquisition of
      Vicuron Pharmaceuticals, Inc in the third quarter and $262 million
      related primarily to our acquisition of Idun Pharmaceuticals, Inc. in
      the second quarter.
  4.  Amortization expense related to acquired intangible assets that
      contribute to our ability to sell, manufacture, research, market and
      distribute our products are included in Amortization of intangible
      assets as they benefit multiple business functions. Amortization
      expense related to acquired intangible assets that are associated with
      a single function are included in Cost of sales, Selling,
      informational and administrative expenses or Research and development
      expenses, as appropriate.
  5.  Other (income)/deductions -- net for the fourth quarter and full year
      2006 includes a charge of $320 million related to the impairment of
      the Depo-Provera intangible asset and, for the full year 2005,
      includes a charge of $1.2 billion related to the impairment of the
      Bextra intangible asset.
  6.  Discontinued operations -- net of tax is primarily related to our
      Consumer Healthcare business.
  7.  Provision for taxes on income in the full year 2006 includes a
      downward revision ($124 million) of the estimated tax costs related to
      repatriation of foreign earnings in 2005 and tax benefits associated
      with the resolution of certain tax positions ($441 million).  Full
      year 2005 includes tax benefits associated with the resolution of
      certain tax positions ($586 million) and a tax provision related to
      the repatriation of foreign earnings of $1.7 billion.



                   PFIZER INC AND SUBSIDIARY COMPANIES
RECONCILIATION FROM REPORTED NET INCOME AND REPORTED DILUTED EARNINGS PER
     SHARE TO ADJUSTED INCOME AND ADJUSTED DILUTED EARNINGS PER SHARE
                                 (UNAUDITED)

  (millions of dollars, except per common share data)

                            Fourth Quarter % Incr./    Full Year    % Incr./
                            2006      2005  (Decr.)  2006     2005   (Decr.)

  Reported net income      $9,449   $2,732   246    $19,337   $8,085   139
  Purchase accounting
   adjustments -- net of
   tax                        899      569    58      3,131    3,967   (21)
  Acquisition-related
   costs -- net of tax          5      214   (98)        14      599   (98)
  Discontinued operations
   -- net of tax           (7,960)    (155)   M+     (8,313)    (498)   M+
  Cumulative effect of a
   change in accounting
   principles -- net of tax     -       23     *          -       23     *
  Certain significant
   items -- net of tax        654      208   214        813    2,293   (65)
  Adjusted income          $3,047   $3,591   (15)   $14,982  $14,469     4

  Reported diluted
   earnings per common
   share                    $1.32    $0.37   257      $2.66    $1.09   144
  Purchase accounting
   adjustments -- net of
   tax                       0.13     0.08    63       0.43     0.54   (20)
  Acquisition-related
   costs -- net of tax          -     0.03     *          -     0.08     *
  Discontinued operations
   -- net of tax            (1.11)   (0.02)   M+      (1.14)   (0.07)   M+
  Cumulative effect of a
   change in accounting
   principles -- net of tax     -        -     *          -        -     *
  Certain significant
   items -- net of tax       0.09     0.03   200       0.11     0.31   (65)
  Adjusted diluted
   earnings per common
   share                    $0.43    $0.49   (12)     $2.06    $1.95     6


  *   Calculation not meaningful.
  M+  Change greater than one thousand percent.
  Certain amounts and percentages may reflect rounding adjustments.

  1. The above reconciliation presents the three-month and twelve-month
     periods ended December 31 of each year.  Subsidiaries operating outside
     the United States are included for the three-month and twelve-month
     periods ended November 30 of each year.
  2. Adjusted income and Adjusted diluted earnings per common share as shown
     above reflect the following items:


    (millions of dollars)                   Fourth Quarter      Full Year
                                             2006     2005    2006     2005
    Purchase accounting adjustments:
       In-process research and
        development charges(a)                $322     $-      $835  $1,652
       Intangible amortization and
        other(b)                               806    802     3,220   3,289
       Total purchase accounting
        adjustments, pre-tax                 1,128    802     4,055   4,941
       Income taxes                           (229)  (233)     (924)   (974)
                Total purchase accounting
                 adjustments -- net of tax     899    569     3,131   3,967
    Acquisition-related costs:
       Integration costs(c)                     13    159        21     543
       Restructuring charges(c)                 (1)   149         6     375
       Total acquisition-related costs,
        pre-tax                                 12    308        27     918
       Income taxes                             (7)   (94)      (13)   (319)
               Total acquisition-related
                costs -- net of tax              5    214        14     599
    Discontinued operations:
       Income from discontinued
        operations(d)                         (150)  (230)     (643)   (695)
       Gains on sales of discontinued
        operations(d)                      (10,206)    (5)  (10,243)    (77)
       Total discontinued operations,
        pre-tax                            (10,356)  (235)  (10,886)   (772)
       Income taxes                          2,396     80     2,573     274
                Total discontinued
                 operations -- net of tax   (7,960)  (155)   (8,313)   (498)
    Cumulative effect of a change in
     accounting principles -- net of tax         -     23         -      23
    Certain significant items:
       Asset impairment charges and
        other associated costs(e)              320     24       320   1,240
       Sanofi-aventis research and
        development milestone(f)                 -      -      (118)      -
       Restructuring charges - Adapting
        to Scale(c)                            495    265     1,296     438
       Implementation costs - Adapting
        to Scale(g)                            241    192       788     325
       Gain on disposals of investments
        and other(h)                           (13)  (134)     (173)   (134)
       Total certain significant items,
        pre-tax                              1,043    347     2,113   1,869
       Income taxes                           (389)  (104)     (735)   (654)
       Resolution of certain tax
        positions(i)                             -      -      (441)   (586)
       Tax impact for the repatriation
        of foreign earnings(i)                   -    (35)     (124)  1,664
               Total certain significant
                items -- net of tax            654    208       813   2,293

    Total purchase accounting
     adjustments, acquisition-related
     costs, discontinued operations,
     cumulative effective of a change
     in accounting principles and certain
     significant items -- net of tax       $(6,402)  $859   $(4,355) $6,384

    (a) Included in Acquisition-related in-process research and development
        charges.
    (b) Included primarily in Amortization of intangible assets.
    (c) Included in Restructuring charges and acquisition-related costs.
    (d) Discontinued operations -- net of tax is primarily related to our
        Consumer Healthcare business.
    (e) Included primarily in Other (income)/deductions -- net. For the
        fourth quarter and full year 2006, includes $320 million related to
        the impairment of the Depo-Provera intangible asset, and for the
        full year 2005, includes $1.2 billion related to the impairment of
        the Bextra intangible asset.
    (f) Included in Research and development expenses.
    (g) Included in Cost of sales ($114 million), Selling, informational and
        administrative expenses ($83 million) and Research and development
        expenses ($44 million) for the three months ended December 31, 2006
        and included in Cost of sales ($392 million), Selling, informational
        and administrative expenses ($243 million), Research and development
        expenses ($176 million) and in Other (income)/deductions-net ($23
        million income) for the full year ended December 31, 2006.  Included
        in Cost of sales ($87 million), Selling, informational and
        administrative expenses ($75 million) and Research and development
        expenses ($30 million) for the three months ended December 31, 2005
        and included in Cost of sales ($124 million), Selling, informational
        and administrative expenses ($151 million), Research and development
        expenses ($50 million) for the full year ended December 31, 2005.
    (h) Included in Other (income)/deductions -- net.
    (i) Included in Provision for taxes on income.



                                PFIZER INC
                         SEGMENT/PRODUCT REVENUES
                           FOURTH QUARTER 2006
                          (millions of dollars)

                      WORLDWIDE             U.S.           INTERNATIONAL
                                 %                    %                  %
                2006     2005   Chg   2006    2005   Chg   2006  2005   Chg

  TOTAL
  REVENUES     12,603  12,547    -    6,404  6,609   (3)  6,199  5,938    4

  PHARMA-
  CEUTICAL     11,666  11,653    -    6,055  6,246   (3)  5,611  5,407    4

  - CARDIOVASCULAR
    AND
    METABOLIC
    DISEASES    5,243   5,068    3    2,865  2,787    3   2,378  2,281    4

    LIPITOR     3,335   3,357   (1)   1,945  2,069   (6)  1,390  1,288    8
    NORVASC     1,317   1,244    6      686    613   12     631    631    -
    CARDURA       140     146   (4)       2      2   35     138    144   (4)
    CADUET        115      65   77      109     63   71       6      2  333
    ACCUPRIL/
    ACCURETIC      68      44   56        5    (25)(122)     63     69   (9)
    CHANTIX/
    CHAMPIX        68       -    *       68      -    *       -      -    *

  - CENTRAL
    NERVOUS
    SYSTEM
    DISORDERS   1,251   1,673  (25)     597  1,023  (42)    654    650    1

    ZOLOFT        166     808  (79)      76    653  (88)     90    155  (42)
    LYRICA        353     153  131      214     82  160     139     71   98
    GEODON/
    ZELDOX        210     159   32      176    131   34      34     28   24
    NEURONTIN     120     141  (15)      18     27  (34)    102    114  (11)
    ARICEPT**      98      90    9        -      -    *      98     90    8
    XANAX/
    XR             81     102  (21)      15     35  (59)     66     67   (1)
    RELPAX         81      63   27       52     38   38      29     25   11

  - ARTHRITIS
    AND PAIN      737     650   13      477    402   19     260    248    5

    CELEBREX      540     472   15      412    357   16     128    115   12

  - INFECTIOUS
    AND
    RESPIRATORY
    DISEASES      866   1,111  (22)     256    513  (50)    610    598    2

    ZYVOX         223     164   36      144    118   22      79     46   70
    ZITHROMAX/
    ZMAX          109     402  (73)      (3)   262 (101)    112    140  (20)
    VFEND         148     112   31       49     40   23      99     72   36
    DIFLUCAN      109     128  (15)     (13)    (1)  M+     122    129   (5)

  - UROLOGY       754     727    4      429    410    5     325    317    3

    VIAGRA        450     430    5      222    212    5     228    218    5
    DETROL/
    DETROL LA     290     283    2      201    193    5      89     90   (3)

  - ONCOLOGY      641     497   29      273    167   64     368    330   11

    CAMPTOSAR     235     237   (1)     127    124    3     108    113   (4)
    ELLENCE        76      94  (20)      11     17  (33)     65     77  (17)
    AROMASIN       91      71   29       30     25   23      61     46   33
    SUTENT        104       -    *       69      -    *      35      -    *

  - OPHTHALMOLOGY 396     362    9      123    116    6     273    246   11

    XALATAN/
    XALACOM       391     361    8      123    116    6     268    245    9

  - ENDOCRINE
    DISORDERS     261     266   (2)      67     86  (23)    194    180    7

    GENOTROPIN    209     204    3       61     60    2     148    144    3

  - ALL OTHER   1,127     991   14      746    559   33     381    432  (11)

    ZYRTEC/
    ZYRTEC D      374     327   14      374    327   14       -      -    *

  - ALLIANCE
    REVENUE
    (Aricept,
    Macugen,
    Mirapex,
    Olmetec,
    Rebif and
    Spiriva)      390     308   26      222    183   21     168    125   34

  ANIMAL
  HEALTH          655     630    4      281    283   (1)    374    347    8

  OTHER ***       282     264    7       68     80  (15)    214    184   16

  *   - Calculation not meaningful.
  **  - Represents direct sales under license agreement with Eisai Co.,
         Ltd.
  *** - Includes Capsugel and Pfizer CenterSource.
  M+  - Change greater than one-thousand percent.
  Certain amounts and percentages may reflect rounding adjustments.
  Certain prior year data have been reclassified to conform to the
  current year presentation.



                                PFIZER INC
                         SEGMENT/PRODUCT REVENUES
                            TWELVE MONTHS 2006
                          (millions of dollars)

                     WORLDWIDE                U.S.         INTERNATIONAL
                                %                     %                  %
                2006    2005   Chg    2006   2005    Chg  2006   2005   Chg
  TOTAL
  REVENUES     48,371  47,405    2   25,822 24,751    4  22,549 22,654    -

  PHARMA-
  CEUTICAL     45,083  44,269    2   24,503 23,471    4  20,580 20,798   (1)

  - CARDIOVASCULAR
    AND
    METABOLIC
    DISEASES   19,871  18,732    6   11,124 10,036   11   8,747  8,696    1

    LIPITOR    12,886  12,187    6    7,849  7,401    6   5,037  4,786    5
    NORVASC     4,866   4,706    3    2,500  2,222   13   2,366  2,484   (5)
    CARDURA       538     586   (8)       7      7    -     531    579   (8)
    CADUET        370     185   99      349    179   95      21      6  241
    ACCUPRIL/
    ACCURETIC     266     294  (10)      29     22   37     237    272  (13)
    CHANTIX/
    CHAMPIX       101       -    *      101      -    *       -      -    *

  - CENTRAL
    NERVOUS
    SYSTEM
    DISORDERS   6,038   6,391   (6)   3,635  3,816   (5)  2,403  2,575   (7)

    ZOLOFT      2,110   3,256  (35)   1,752  2,573  (32)    358    683  (47)
    LYRICA      1,156     291  297      717    111   M+     439    180  144
    GEODON/
    ZELDOX        758     589   29      631    483   31     127    106   20
    NEURONTIN     496     639  (22)      91    159  (43)    405    480  (16)
    ARICEPT**     358     346    4        1      -    *     357    346    4
    XANAX/XR      316     409  (23)      70    141  (50)    246    268   (8)
    RELPAX        286     233   23      185    143   30     101     90   11

  - ARTHRITIS
    AND PAIN    2,711   2,386   14    1,781  1,377   29     930  1,009   (8)

    CELEBREX    2,039   1,730   18    1,577  1,267   24     462    463    -

  - INFECTIOUS
    AND
    RESPIRATORY
    DISEASES    3,474   4,770  (27)   1,222  2,449  (50)  2,252  2,321   (3)

    ZYVOX         782     618   27      527    438   20     255    180   42
    ZITHROMAX/
    ZMAX          638   2,025  (69)     210  1,497  (86)    428    528  (19)
    VFEND         515     397   30      178    140   27     337    257   31
    DIFLUCAN      435     498  (13)     (17)   (17)  (3)    452    515  (12)

  - UROLOGY     2,809   2,684    5    1,586  1,497    6   1,223  1,187    3

    VIAGRA      1,657   1,645    1      796    802   (1)    861    843    2
    DETROL/
    DETROL LA   1,100     988   11      769    675   14     331    313    5

  - ONCOLOGY    2,191   1,996   10      887    701   26   1,304  1,295    1

    CAMPTOSAR     903     910    -      491    471    4     412    439   (6)
    ELLENCE       312     367  (15)      54     73  (26)    258    294  (12)
    AROMASIN      320     247   30      113     85   34     207    162   27
    SUTENT        219       -    *      167      -    *      52      -    *

  - OPHTHAL-
    MOLOGY      1,461   1,373    6      483    432   12     978    941    4

    XALATAN/
    XALACOM     1,453   1,372    6      483    432   12     970    940    3

  - ENDOCRINE
    DISORDERS     985   1,049   (6)     258    341  (24)    727    708    3

    GENOTROPIN    795     808   (2)     230    239   (4)    565    569   (1)

  - ALL OTHER   4,169   3,823    9    2,711  2,205   23   1,458  1,618  (10)

    ZYRTEC/
    ZYRTEC D    1,569   1,362   15    1,569  1,362   15       -      -    *

  - ALLIANCE
    REVENUE
    (Aricept,
    Macugen,
    Mirapex,
    Olmetec,
    Rebif and
    Spiriva)    1,374   1,065   29      816    617   32     558    448   25

  ANIMAL
  HEALTH        2,311   2,206    5    1,032    993    4   1,279  1,213    5

  OTHER ***       977     930    5      287    287    -     690    643    7


   *   - Calculation not meaningful.
   **  - Represents direct sales under license agreement with Eisai Co.,
         Ltd.
   *** - Includes Capsugel and Pfizer CenterSource.

   M+  - Change greater than one-thousand percent.
   Certain amounts and percentages may reflect rounding adjustments.
   Certain prior year data have been reclassified to conform to the current
   year presentation.

                                PFIZER INC
                    SUPPLEMENTAL FINANCIAL INFORMATION

  1) Revenue Growth

Fourth-quarter 2006 revenues were substantially unchanged and full-year 2006 revenues increased 2% compared to the same periods in 2005, due primarily to the solid aggregate performance of our broad portfolio of patent-protected medicines and an aggregate year-over-year increase in revenues from new products launched in 2004, 2005, and 2006, largely offset by the impact of the loss of U.S. exclusivity on Zoloft in June 2006, as well as on Zithromax in November 2005.

Revenues in the fourth quarter of 2006 were also impacted by the weakening of the U.S. dollar relative to many foreign currencies (especially the euro), which increased revenue by $164 million. Revenues for the full-year of 2006 were impacted by the strengthening of the U.S. dollar relative to many foreign currencies (especially the euro and Japanese yen), which decreased revenue by $279 million.

2) Change in Cost of Sales

The Cost of Sales pre-tax component of adjusted income(1) increased 11% in the fourth quarter and 3% for the full year of 2006 compared to the same periods in 2005. Reported cost of sales increased 12% in the fourth quarter of 2006 and increased 6% for the full year of 2006 compared to the same periods in 2005. The increase in the fourth quarter primarily reflects the timing of implementation of inventory management initiatives, the impact of foreign exchange, and charges related to certain asset writedowns. Full-year cost of sales growth reflects these same considerations, partially offset by the impact of changes in 2006 sales mix during the first half of the year and the realization of savings associated with our Adapting to Scale (AtS) productivity initiatives, among other factors. In addition, cost of sales includes charges of $114 million and $87 million related to our AtS productivity initiative for the fourth quarter of 2006 and 2005, and $392 million and $124 million for the twelve months ended December 31, 2006 and 2005.

3) Change in Selling, Informational & Administrative (SI&A) Expenses and Research & Development (R&D) Expenses

SI&A expenses increased 5% and 2% in the fourth quarter and full year of 2006, compared to the same periods in 2005.

R&D expenses, excluding acquisition-related in-process research and development charges (IPR&D), grew 22% and 5% in the fourth quarter and full year of 2006 compared to the same periods in 2005. The increases reflect timing considerations associated with the advancement of development programs for pipeline products, expenditures associated with in-licensing of a new compound, and the establishment of various research collaborations with third parties, among other factors. IPR&D charges of $322 million primarily related to the acquisition of PowderMed Ltd. were recorded in the fourth quarter of 2006. Full-year 2006 IPR&D charges were $835 million, primarily related to the acquisition of PowderMed, Ltd. and Rinat Neuroscience Corp. In full-year 2005, we recorded IPR&D charges of $1.4 billion for the acquisition of Vicuron Pharmaceuticals, Inc., as well as $262 million, related primarily to our acquisition of Idun Pharmaceuticals Inc.

SI&A and R&D expenses include charges of $83 million and $44 million related to AtS implementation costs in the fourth quarter of 2006, and $243 million and $176 million in the full year of 2006. SI&A and R&D expenses included charges of $75 million and $30 million related to AtS implementation costs in the three months ended December 31, 2005, and $151 million and $50 million in the twelve months of 2005.

4) Savings and Costs Relating to Productivity Initiatives

Our Adapting to Scale (AtS) productivity initiative, launched in the first quarter of 2005, involves a comprehensive, multi-year review of our processes, organizations, systems, and decision making to identify and capitalize on opportunities to make the company more effective and efficient. Savings realized during 2006 were approximately $2.6 billion for the full year of 2006, exceeding our original goal of about $2.0 billion for the year.

Costs relating to the AtS productivity initiative were $736 million and $2.1 billion for the fourth quarter and full year of 2006, compared to $457 million and $763 million in the fourth quarter and full year of 2005. Fourth- quarter and full-year 2006 costs included a provision for reductions in the U.S. pharmaceutical field force.

  5) Other Income and Other Deductions


  ($ millions)                Fourth Quarter               Full Year
                            2006         2005*         2006        2005*

  Net Interest (Income)/
   Expense                 $(160)       $(110)       $(437)       $(269)
  Asset Impairment Charges   320            7          320        1,159

  Royalties                 (117)         (87)        (395)        (320)

  Gains on Disposals of
   Investments/ Product
   Lines                      (9)        (114)        (233)        (172)

  Other, Net                  20           (2)        (159)          (1)

  Other (Income)/Deductions
  -Net                       $54        $(306)       $(904)        $397


  * Certain 2005 amounts were reclassified to conform to the 2006
    presentation.

In the fourth quarter of 2006, we recorded a charge of $320 million related to the impairment of our Depo-Provera intangible asset. In connection with the decision to suspend sales of Bextra in the first quarter of 2005, we recorded a charge of $1.1 billion relating to the impairment of our Bextra intangible asset.

  6) Effective Tax Rate


                          Fourth Quarter          Full Year

  2005 Reported(a)            17.1%                  29.4%(c)

  2005 Adjusted(a)(b)         21.8%                  21.8%

  2006 Reported(a)            13.0%(d)               15.3%(e)

  2006 Adjusted(a)(b)         21.7%(f)               22.0%(f)


  (a) 2005 and 2006 Reported and Adjusted are based on income from
      continuing operations and therefore exclude the results of our
      divested Consumer Healthcare business.
  (b) Used in the calculation of Adjusted income(1).
  (c) The reported tax rate in 2005 reflects tax costs associated with
      our program in 2005 to repatriate foreign earnings under the
      American Jobs Creation Act; the impact of a $1.4 billion charge
      for acquired IPR&D, which is not deductible for tax purposes; and
      the favorable resolution of certain tax positions.
  (d) The reported tax rate for the fourth quarter of 2006 reflects the
      retroactive reenactment of the R&D tax credit in the U.S. in
      December 2006, the full amount of which was recorded in the
      fourth quarter of 2006.
  (e) The reported tax rate for full-year 2006 reflects the favorable
      resolution of certain tax positions, a favorable tax-law change
      in the first quarter, a downward revision of the estimated tax
      costs related to the repatriation of foreign earnings in 2005,
      the retroactive reenactment of the R&D tax credit in the U.S. in
      December 2006, and the impact of the sale of our Consumer
      Healthcare business, among other factors.
  (f) The fourth-quarter and full-year 2006 effective tax rate on
      Adjusted income(1) benefited from the retroactive reenactment of the
      R&D tax credit in the U.S. in December 2006.  The full amount of
      this benefit was recorded in the fourth quarter of 2006.

7) Reconciliation of Original* Forecasted 2006 Adjusted Income(1) and Adjusted Diluted EPS(1) to Original* Forecasted 2006 Reported Net Income and Reported Diluted EPS

                                                 Full Year 2006 Original*
                                                        Forecast
  ($ billions, except per-share amounts)        Net Income(a) Diluted EPS(a)
  Income/(Expense)
  Forecasted Adjusted Income/Diluted EPS(1)         ~$14.5         ~$1.93
  Purchase Accounting Impacts, Net of Tax            (2.3)         (0.31)
  Adapting-to-Scale Costs, Net of Tax            (1.4 - 1.7)  (0.19 - 0.23)
  Income From Discontinued Operations,
   Net of Tax(b)                                      0.5           0.07
  Resolution of Certain Tax Positions                 0.4           0.06
  Forecasted Reported Net Income/Diluted
   EPS                                        ~ $11.4 - $11.7 ~$1.52 - $1.56


  * Adapted from forecast disclosed on Form 8-K, filed on February 10,
    2006.

  (a) Forecasts in the table exclude the effects of business-
      development transactions not completed as of December 31, 2005.
      Forecasts in the table do not include the potential impact from a
      substantial prospective gain on the divestiture of our Consumer
      Healthcare business, as well as costs related to our recently
      announced sales-force restructuring.
  (b) Primarily reflects the reclassification of our Consumer
      Healthcare business to discontinued operations.

  8) Consumer Healthcare

We completed the sale of our Consumer Healthcare business on December 20, 2006. Revenues from our Consumer Healthcare business were $1.1 billion and $4.0 billion for the fourth quarter and full year of 2006, respectively. Income from discontinued operations -- net of tax, was $8.3 billion for the full year of 2006, including the fourth-quarter gain on sale of our Consumer Healthcare business of $7.9 billion.

9) Share-Purchase Program

In total, the Company purchased approximately 266 million shares at a total cost of about $7 billion during 2006, including about 94 million shares (about $2.5 billion) in the fourth quarter. In June 2006, the Board of Directors increased our share-purchase authorization from $5 billion to $18 billion.

  (1) "Adjusted income" and "adjusted diluted earnings per share (EPS)"
      are defined as reported net income and reported diluted EPS
      excluding purchase-accounting adjustments, acquisition-related
      costs, discontinued operations, cumulative effect of a change in
      accounting principles and certain significant items.  As
      described under Adjusted Income in the Management's Discussion
      and Analysis of Financial Condition and Results of Operations
      section of Pfizer's Form 10-Q for the quarterly period ended
      October 1, 2006, management uses adjusted income, among other
      factors, to set performance goals and to measure the performance
      of the overall company.  We believe that investors' understanding
      of our performance is enhanced by disclosing this measure.
      Reconciliations of fourth-quarter and full-year 2006 and 2005
      adjusted income and adjusted diluted EPS to reported net income
      and reported diluted EPS as well as a reconciliation of the
      original $1.93 estimate of full-year 2006 adjusted diluted EPS to
      reported diluted EPS, are provided in the materials accompanying
      this report.  The adjusted income and adjusted diluted EPS
      measures are not, and should not be viewed as, substitutes for U.S.
      GAAP net income and diluted EPS.


DISCLOSURE NOTICE: The information contained in this document and the attachments is as of January 22, 2007. The Company assumes no obligation to update any forward-looking statements contained in this document or the attachments as a result of new information or future events or developments.

This document and the attachments contain forward-looking information about the Company's financial results and estimates, business plans and prospects, in-line products, and product candidates that involve substantial risks and uncertainties. You can identify these statements by the fact that they use words such as "will," "anticipate," "estimate," "expect," "project," "intend," "plan," "believe," "target," "forecast", and other words and terms of similar meaning in connection with any discussion of future operating or financial performance or business plans and prospects. Among the factors that could cause actual results to differ materially are the following: the success of research and development activities; decisions by regulatory authorities regarding whether and when to approve our drug applications as well as their decisions regarding labeling and other matters that could affect the availability or commercial potential of our products; the speed with which regulatory authorizations, pricing approvals, and product launches may be achieved; the success of external business development activities; competitive developments, including with respect to competitor drugs and drug candidates that treat diseases and conditions similar to those treated by our in-line drugs and drug candidates; the ability to successfully market both new and existing products domestically and internationally; difficulties or delays in manufacturing; trade buying patterns; the ability to meet generic and branded competition after the loss of patent protection for our products and competitor products; the impact of existing and future regulatory provisions on product exclusivity; trends toward managed care and health care cost containment; possible U.S. legislation or regulatory action affecting, among other things, pharmaceutical pricing and reimbursement, including under Medicaid and Medicare, the importation of prescription drugs that are marketed outside the U.S. and sold at prices that are regulated by governments of various foreign countries, and the involuntary approval of prescription medicines for over-the-counter use; the impact of the Medicare Prescription Drug, Improvement and Modernization Act of 2003; legislation or regulations in markets outside the U.S. affecting product pricing, reimbursement, or access; contingencies related to actual or alleged environmental contamination; claims and concerns that may arise regarding the safety or efficacy of in-line products and product candidates; legal defense costs, insurance expenses, settlement costs, and the risk of an adverse decision or settlement related to product liability, patent protection, governmental investigations, ongoing efforts to explore various means for resolving asbestos litigation, and other legal proceedings; the Company's ability to protect its patents and other intellectual property both domestically and internationally; interest rate and foreign currency exchange rate fluctuations; governmental laws and regulations affecting domestic and foreign operations, including tax obligations; changes in generally accepted accounting principles; any changes in business, political, and economic conditions due to the threat of future terrorist activity in the U.S. and other parts of the world, and related U.S. military action overseas; growth in costs and expenses; changes in our product, segment, and geographic mix; and the impact of acquisitions, divestitures, restructurings, product withdrawals, and other unusual items, including our ability to realize the projected benefits of our Adapting to Scale multi-year productivity initiative, including the projected benefits of the broadening of this initiative over the next few years. A further list and description of these risks, uncertainties, and other matters can be found in the Company's Annual Report on Form 10-K for the fiscal year ended December 31, 2005, and in its reports on Forms 10-Q and 8-K.

This document may include discussion of certain clinical studies relating to various in-line products and/or product candidates. These studies typically are part of a larger body of clinical data relating to such products or product candidates, and the discussion herein should be considered in the context of the larger body of data.

Company News On-Call: Pfizer's press releases are available through PRNewswire's Company News On-Call service on PRN's Web Site. Visithttp://www.prnewswire.com/comp/688250.html

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