Bristol-Myers Squibb Company Reports Financial Results for the Third Quarter and First Nine Months of 2005, Reflecting Ongoing Investments in Strategy Aimed at Delivering Sustainable Growth

- Records GAAP EPS of $0.49 and Non-GAAP EPS of $0.31 for the Third Quarter

Bristol-Myers Squibb Company Reports Financial Results for the Third Quarter and First Nine Months of 2005, Reflecting Ongoing Investments in Strategy Aimed at Delivering Sustainable Growth

NEW YORK, Oct. 28 /PRNewswire-FirstCall/ -- Bristol-Myers Squibb Company today reported financial results for the quarter and nine months ended September 30, 2005 and provided further earnings guidance for the full year.

The company posted third quarter 2005 net sales from continuing operations of $4.8 billion, which were unchanged from the same period last year. Increased sales of newer pharmaceutical products, as well as growth in the Nutritionals segment in the third quarter of 2005 were offset by the impact of continued exclusivity losses among older pharmaceutical products.

The company reported third quarter 2005 net earnings from continuing operations of $964 million, or $0.49 per diluted share, under U.S. Generally Accepted Accounting Principles (GAAP), compared to $755 million, or $0.38 per diluted share for the same period last year.

Bristol-Myers Squibb reported third quarter 2005 net earnings from continuing operations of $602 million, or $0.31 per diluted share, on a non- GAAP basis excluding specified items, compared to $865 million, or $0.44 per diluted share for the same period last year.

"Our strategy remains on track and our newer products delivered solid global sales performance during the quarter," said Peter R. Dolan, chief executive officer, Bristol-Myers Squibb. "The company's full-year expectations remain within our range and include our decision to make incremental, targeted investments, in addition to the spending programs we identified at mid year, to further support key products and pipeline priorities. And, our robust portfolio sets the stage for sustained growth for the future, with four new products launched in three years, three drugs currently under U.S. regulatory consideration, and another possible filing within the next three months."

For the nine months ended September 30, 2005, net sales from continuing operations remained constant at $14.2 billion compared to the same period last year. Under GAAP, net earnings from continuing operations in the nine months ended September 30, 2005 were $2.5 billion, or $1.27 per diluted share compared to $2.2 billion, or $1.14 per diluted share for the same period last year. On a non-GAAP basis excluding specified items, Bristol-Myers Squibb reported net earnings from continuing operations of $2.2 billion, or $1.12 per diluted share for the nine months ended September 30, 2005, compared to $2.6 billion, or $1.31 per diluted share for the same period last year.

INCREMENTAL, TARGETED INVESTMENTS AND A ROBUST PIPELINE

Bristol-Myers Squibb is increasing investments behind targeted marketing programs for pharmaceutical products expected to drive future growth in serious disease areas with significant unmet medical need. For example, the company is complementing its efforts focused on high-value primary care physicians and specialists with direct-to-consumer marketing that includes expanded advertising for PLAVIX(R), and the first-ever print ad campaign for ABILIFY(R).

Bristol-Myers Squibb is also increasing research and development investments, in line with the low double-digit annual growth rate that continues to be planned for 2005. During the third quarter, among Bristol- Myers Squibb's full-development programs, ORENCIA(R), a potential therapy for rheumatoid arthritis was recommended for approval by the U.S. Food and Drug Administration (FDA) Arthritis Advisory Committee and saxagliptin, the company's DPP4 inhibitor for the potential treatment of diabetes transitioned to Phase III.

As previously disclosed, on October 18, 2005, the FDA issued an approvable letter for PARGLUVA(TM) (muraglitazar), the company's investigational oral medicine for the treatment of type 2 diabetes. The FDA requested additional information from ongoing clinical trials to more fully address the cardiovascular safety profile of muraglitazar. Yesterday, Bristol-Myers Squibb announced that the company and its partner, Merck & Co., Inc., have determined that to receive regulatory approval and to achieve commercial success, additional studies may be required because the ongoing trials were not designed to answer questions raised by the FDA. The additional studies could take approximately five years to complete. Bristol-Myers Squibb also announced yesterday that it agreed to begin discussions with Merck to terminate the companies' collaborative agreement. Bristol-Myers Squibb will continue discussions with the FDA and will consider a range of options including conducting additional studies or terminating further development of muraglitazar.

Looking ahead to December, Bristol-Myers Squibb plans to present Phase II data on dasatinib, a SRC/ABL Kinase Inhibitor being investigated for the treatment of chronic myelogenous leukemia (CML), at the American Society of Hematology (ASH) annual meeting. The company continues to expect a possible dasatinib filing in the next three months.

  THIRD QUARTER RESULTS

  * Third quarter 2005 net sales from continuing operations remained
    constant at $4.8 billion compared to the same period last year,
    reflecting a 1% favorable impact of foreign exchange rate fluctuations
    and a 1% increase in average selling prices, offset by a 2% decrease in
    volume.  U.S. net sales of $2.7 billion remained constant for the
    quarter compared to 2004, while international net sales decreased 1% to
    $2.1 billion, including a 2% favorable foreign exchange impact.

  * Marketing, selling and administrative expenses increased by 7% to $1.3
    billion in the third quarter of 2005 primarily due to higher legal
    costs, higher pension expenses reflecting increased amortization of
    unrecognized net losses as well as changes in actuarial assumptions, and
    increased expenditures on late-stage compounds.

  * Bristol-Myers Squibb continues to shift advertising and product
    promotion investments from mature brands to products expected to drive
    future growth.  The company increased advertising and promotion spending
    by 7% to $349 million in the third quarter of 2005 from $325 million in
    the same period last year, primarily for increased investments behind
    PLAVIX(R) and the launch of BARACLUDE(TM), in addition to increased
    costs associated with pre-launch activities.

  * Research and development expenses increased by 9% to $669 million in the
    third quarter of 2005 from $615 million in the same period last year.
    Excluding $11 million consisting primarily of milestone payments in the
    third quarter of 2004, research and development grew 11%.  This increase
    reflects continued investments in other late-stage compounds.
    Investment in pharmaceutical research and development equaled 16.3% of

    pharmaceutical sales in the third quarter of 2005, compared to 14.7% in
    the same period last year.

  * The company completed the sale of its U.S. and Canadian Consumer
    Medicines business and related assets in the third quarter of 2005. The
    company received cash proceeds of $661 million in cash, of which $15
    million is attributable to a post-closing supply arrangement.  As a
    result of this transaction, the company recorded a pre-tax gain of $569
    million ($370 million net of tax) in the third quarter of 2005.

  INCOME TAXES

The effective income tax rate on earnings from continuing operations before minority interest and income taxes was 31.2% and 20.9% for the three months ended September 30, 2005 and 2004, respectively. The higher effective tax rate was primarily driven by a $569 million pre-tax gain recognized on the sale of the U.S. and Canadian Consumer Medicines business and related assets in the third quarter of 2005.

SPECIFIED ITEMS

In the three months ending September 30, 2005 and 2004, the company recorded specified income and expense items that affected the comparability of the results.

  The pre-tax specified items in 2005 included:

  * $569 million gain on sale of the U.S. and Canadian Consumer Medicines
    business and related assets
  * $31 million net charges primarily associated with accelerated
    depreciation and asset impairment
  * $26 million income from insurance recoveries, related to various
    litigation matters

  The pre-tax specified items in 2004 included:

  * $105 million related to accelerated depreciation and termination
    benefits
  * $36 million charges for litigation matters
  * $8 million primarily related to a milestone payment

For additional information on specified items, see Appendix 1. Details reconciling these non-GAAP amounts with GAAP amounts including specified items are provided in supplemental materials available on the company's website.

PHARMACEUTICALS

Worldwide pharmaceutical sales decreased 2% to $3.8 billion in the third quarter of 2005 compared to the same period last year.

U.S. pharmaceutical sales decreased 3% to $2.1 billion in the third quarter of 2005 compared to the same period last year, primarily due to the continued impact of exclusivity losses for PARAPLATIN(R) and VIDEX(R) EC, increased competition for PRAVACHOL(R), partially offset by the continued growth of PLAVIX(R), ABILIFY(R), REYATAZ(R) and ERBITUX(R). In aggregate, estimated wholesaler inventory levels of the company's key pharmaceutical products sold by the U.S. Pharmaceutical business at the end of the third quarter were down from the end of the second quarter of 2005, by approximately one-tenth of a month to two-and-a-half weeks. Individually, estimated wholesaler inventory levels of major brands such as PLAVIX(R), PRAVACHOL(R) and AVAPRO(R)/AVALIDE(R) decreased to approximately two weeks.

Also in the third quarter of 2005, the company negotiated amendments to its inventory management agreements with its three largest wholesalers, which together account for over 90% of U.S. pharmaceutical net sales. The amendments extended the original agreements through December 31, 2005 and established lower limits than the original agreements for inventory levels of company pharmaceutical products held by the wholesalers. The company is in discussions to extend the agreements for periods beyond 2005. Over the long- term, if extended on similar terms, the company should benefit from reduced sales volatility due to lower levels of fluctuating inventory build and work down in the wholesaler channel.

International pharmaceutical sales remained constant, including a 2% favorable foreign exchange impact, at $1.7 billion for the third quarter of 2005 compared to the same period last year. The sales decrease excluding the favorable impact of foreign exchange was primarily due to a decline in TAXOL(R) and PRAVACHOL(R) sales resulting from increased generic competition, partially offset by increased sales of newer products including REYATAZ(R) and ABILIFY(R), as well as growth of PLAVIX(R).

Pharmaceutical Growth Drivers

Worldwide sales of the products that the company views as current and future growth drivers increased to 47% of worldwide pharmaceutical sales in the third quarter of 2005, compared to 39% in the same period last year. U.S. sales of these growth drivers accounted for approximately 67% and 58% of total U.S. pharmaceutical sales in the third quarter of 2005 and 2004, respectively.

  * Sales of PLAVIX(R), a platelet aggregation inhibitor that is part of the
    company's alliance with Sanofi-Aventis, increased 9%, including a 1%
    favorable foreign exchange impact, to $980 million in the third quarter
    of 2005 from $902 million in the same period last year, primarily due to
    increased demand, partially offset by a reduction in U.S. wholesale
    inventory levels in 2005.  Total U.S. prescription demand grew
    approximately 12% compared to 2004.

  * Sales of AVAPRO(R)/AVALIDE(R), an angiotensin II receptor blocker for
    the treatment of hypertension, also part of the Sanofi-Aventis alliance,
    increased 4%, including a 2% favorable foreign exchange impact, to $251
    million in the third quarter of 2005 from $241 million in the same
    period last year primarily due to increased demand, partially offset by
    a reduction in U.S. wholesaler inventory levels in 2005.  Total U.S.
    prescription growth increased approximately 11% compared to 2004.

  * Total revenue for ABILIFY(R) increased 58% to $260 million in the third
    quarter of 2005 from $165 million in the same period last year,
    primarily due to strong growth in domestic demand and the continued
    growth in Europe, which achieved sales of $40 million in the third
    quarter of 2005.  Estimated U.S. wholesaler inventory levels at the end
    of the third quarter increased to nine-tenths of a month.  Total U.S.
    prescription demand grew approximately 38% compared to 2004.  ABILIFY(R)
    is an antipsychotic agent used for the treatment of schizophrenia, acute
    bipolar mania and Bipolar I Disorder.  Total revenue for ABILIFY(R)
    primarily consists of alliance revenue recorded by the company as net
    sales based on its 65% share of net sales in copromotion countries with
    Otsuka Pharmaceutical Co. Ltd.

  * Sales of REYATAZ(R), a protease inhibitor for the treatment of HIV,
    increased 66%, including a 1% favorable foreign exchange impact, to $176
    million in the third quarter of 2005 from $106 million in the same
    period last year, primarily due to increased demand.  REYATAZ(R) has
    achieved a monthly new prescription share of the U.S. protease
    inhibitors market of approximately 31%.  European sales increased 152%
    to $53 million in the third quarter of 2005 from $21 million in the same
    period last year.

  * Sales of ERBITUX(R), sold almost exclusively in the United States,
    increased 27% to $107 million in the third quarter of 2005 from $84
    million in the same period last year.  ERBITUX(R) also surpassed $500
    million in total net sales since its launch in February 2004, with more
    than 16,500 patients receiving the metastatic colorectal cancer therapy.
    ERBITUX(R) is marketed by the company under a distribution and
    copromotion agreement with ImClone Systems Incorporated.

  * BARACLUDE(TM), Bristol-Myers Squibb's internally developed therapy for
    hepatitis B, has generated domestic sales of $7 million since its U.S.
    launch in April 2005.  BARACLUDE(TM) received approvals from\
    international authorities in Brazil, Indonesia and Argentina during the
    third quarter of 2005.

  Other Pharmaceuticals

Pharmaceutical products other than those the company views as future growth drivers tend to be more mature products, many of which are subject to exclusivity losses.

  * Sales of PRAVACHOL(R) decreased 12% to $527 million in the third quarter
    of 2005 from $598 million in the same period last year.  U.S.
    PRAVACHOL(R) sales decreased 7% to $297 million in the third quarter of
    2005 from $318 million in the same period last year, primarily due to
    lower demand resulting from increased competition and the related
    reduction in wholesaler inventory levels, partially offset by lower
    managed healthcare rebates in 2005.  Total U.S. prescriptions declined
    by 18% compared to 2004.  International sales decreased 18%, including a
    1% favorable foreign exchange impact, to $230 million, reflecting
    generic competition in key European markets.

  * Sales of TAXOL(R), an anti-cancer agent sold almost exclusively in non-
    U.S. markets, decreased 28%, including a 1% favorable foreign exchange
    impact, to $175 million in the third quarter of 2005 from $243 million
    in the same period last year, primarily as a result of increased generic
    competition in Europe.

  * Sales of SUSTIVA(R), a non-nucleoside reverse transcriptase inhibitor
    for the treatment of HIV, increased 8% to $170 million in the third
    quarter of 2005 from $157 million in the same period last year,
    primarily due to U.S. prescription growth of approximately 6% for the
    third quarter of 2005.

  * Sales of PARAPLATIN(R), an anticancer agent, decreased 76% to $42
    million in the third quarter of 2005 from $177 million in the same
    period last year due to increased generic competition.

  NUTRITIONALS AND RELATED HEALTHCARE

Bristol-Myers Squibb's Nutritionals and Related Healthcare segments posted combined third quarter 2005 revenues of $989 million compared to $930 million in the same period in 2004. The two segments continue to generate a significant portion of Bristol-Myers Squibb's revenues, contributing a combined 21% of third quarter 2005 sales.

  Nutritionals

  * Worldwide Nutritional sales increased 13%, including a 2% favorable
    foreign exchange impact, to $547 million in the third quarter of 2005
    from $484 million in the same period last year.

  * U.S. Nutritional sales increased 16% to $266 million, primarily due to
    increased sales of ENFAMIL(R), the company's best-selling infant
    formula.  International Nutritional sales increased 11% to $281 million,
    including a 4% favorable foreign exchange impact, primarily due to
    increased sales of products for toddlers and children.

  Related Healthcare

  * ConvaTec sales increased 5%, including a 1% favorable foreign exchange
    impact, to $250 million from $237 million in 2004.  Sales of wound
    therapeutic products increased 5% including a 1% favorable foreign
    exchange impact, to $104 million from $99 million in the last year,
    primarily due to increased sales of AQUACEL(R).


  * Medical Imaging sales increased 3% including a 1% favorable foreign
    exchange impact, to $150 million from $145 million in 2004, primarily
    driven by increased sales of CARDIOLITE(R).

  * Consumer Medicines sales were $42 million in the third quarter of 2005
    compared to $64 million in the same period in 2004.  During the third
    quarter of 2005, the company completed the sale of its U.S. and Canadian
    Consumer Medicines business and related assets.

  2005 EPS GUIDANCE

Bristol-Myers Squibb updated 2005 full year earnings guidance of fully- diluted earnings per share from continuing operations to the middle of its previously disclosed $1.35 to $1.45 range, on an adjusted non-GAAP basis which excludes specified items as discussed under "Use of Non-GAAP Financial Information."

The company adjusted its estimate of fully diluted earnings per share when adding back exclusions -- such as milestone payments in connection with previously announced external development, cost of early debt retirement, litigation settlements (including related insurance recoveries for significant legal proceedings), the gain on sale of business and restructurings activities from continuing operations -- to $1.48 to $1.58, from $1.49 to $1.59. This guidance range excludes the impact of recognizing the remaining deferred income from the potential termination of the collaborative agreement with Merck.

Factors that may cause variation in the company's earnings estimates and other risks and uncertainties, are discussed in the company's "Statement on Cautionary Factors," below, and its Securities and Exchange Commission filings.

The company and its subsidiaries are the subject of a number of significant pending lawsuits, claims, proceedings and investigations. It is not possible at this time reasonably to assess the final outcome of these investigations or litigations. Management continues to believe, as previously disclosed, that during the next few years, the aggregate impact, beyond current reserves, of these and other legal matters affecting the company is reasonably likely to be material to the company's results of operations and cash flows, and may be material to its financial condition and liquidity. The company's expectations for the next several years described above do not reflect the potential impact of litigation on the company's results of operations.

For additional discussion of legal matters including PLAVIX(R) patent litigation, see "Item 8. Financial Statements and Supplementary Data-Note 21 Legal Proceedings and Contingencies" in the company's Form 10-K Annual Report for 2004.

Use of Non-GAAP Financial Information

This press release contains non-GAAP earnings per share information adjusted to exclude certain costs, expenses, gains and losses and other specified items. Among the items in GAAP earnings but excluded for purposes of determining adjusted earnings are: gains or losses from sale of product lines, from sale or write-down of equity investments and from discontinuations of operations; restructuring and similar charges; charges and recoveries relating to significant legal proceedings; copromotion or alliance charges and payments for in-process research and development which under GAAP are immediately expensed rather than amortized over the life of the agreement. This information is intended to enhance an investor's overall understanding of the company's past financial performance and prospects for the future. For example, non-GAAP earnings per share information is an indication of the company's baseline performance before items that are considered by the company to be not reflective of the company's operational results. In addition, this information is among the primary indicators the company uses as a basis for evaluating company performance, allocating resources, setting incentive compensation targets, and planning and forecasting of future periods. This information is not intended to be considered in isolation or as a substitute for diluted earnings per share prepared in accordance with GAAP.

Statement on Cautionary Factors

This press release contains certain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 regarding, among other things, statements relating to goals, plans and projections regarding the company's financial position, results of operations, market position, product development and business strategy. These statements may be identified by the fact that they use words such as "anticipate", "estimates", "should", "expect", "guidance", "project", "intend", "plan", "believe" and other words and terms of similar meaning in connection with any discussion of future operating or financial performance. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual outcomes and results to differ materially from current expectations. These factors include, among other things, market factors, competitive product development, pricing controls and pressures (including changes in rules and practices of managed care groups and institutional and governmental purchasers), judicial decisions and governmental laws and regulations related to Medicare, Medicaid and healthcare reform, pharmaceutical rebates and reimbursement, claims and concerns that may arise regarding the safety and efficacy of in-line products and product candidates, changes to wholesaler inventory levels, governmental regulations and legislation, difficulties and delays in product development, manufacturing and sales, patent positions and litigation, including the outcome of the PLAVIX(R) litigation in the U.S. and the expiration of patents on certain other products, and the impact and result of governmental investigations. There can be no guarantees with respect to pipeline products that future clinical studies will support the data described in this release, that the products will receive necessary regulatory approvals, or that they will prove to be commercially successful. For further details and a discussion of these and other risks and uncertainties, see the company's Securities and Exchange Commission filings. The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

Company and Conference Call Information

Bristol-Myers Squibb is a global pharmaceutical and related health care products company whose mission is to extend and enhance human life.

There will be a conference call on October 28, 2005 at 9:00 a.m. (EDT) during which company executives will address inquiries from investors and analysts. Investors and the general public are invited to listen to a live webcast of the call at http://www.bms.com/ir or by dialing 719-457-2625. Materials related to the call will be available at the same Web site prior to the call.

For more information, contact: Tony Plohoros, 212-546-4379, or Jeffrey Schoenborn, 212-546-2846, Communications, or John Elicker, 212-546-3775, or Blaine Davis, 212-546-4631, Investor Relations.

   ABILIFY(R) is the trademark of Otsuka Pharmaceutical Company, Ltd.
   AVAPRO(R), AVALIDE(R) and PLAVIX(R) are trademarks of Sanofi-Aventis
   Erbitux(R) is a trademark of ImClone Systems Incorporated
   GLUCOPHAGE(R), GLUCOPHAGE(R) XR and GLUCOVANCE(R) are registered
    trademarks of Merck Sante, S.A.S., an associate of Merck KGaA of
   Darmstadt, Germany


                       BRISTOL-MYERS SQUIBB COMPANY
                     NET SALES BY OPERATING SEGMENTS
     FOR THE THREE AND NINE MONTHS ENDED SEPTEMBER 30, 2005 AND 2004
                   (Unaudited, in millions of dollars)

                                         Three Months     Nine Months
                                       Ended September  Ended September
                                             30,              30,
                                         2005    2004    2005     2004

  Pharmaceuticals                       $3,778  $3,848  $11,242  $11,414
  Nutritionals                             547     484    1,621    1,496
  Related Healthcare                       442     446    1,325    1,313
  Net Sales from Continuing Operations  $4,767  $4,778  $14,188  $14,223


                       BRISTOL-MYERS SQUIBB COMPANY
                            SELECTED PRODUCTS
     FOR THE THREE AND NINE MONTHS ENDED SEPTEMBER 30, 2005 AND 2004
       (Unaudited, in millions of dollars except prescription data)

The following tables set forth worldwide and U.S. reported net sales for selected products for the three and nine months ended September 30, 2005 compared to the three and nine months ended September 30, 2004. In addition, the tables include, where applicable, the estimated total (both retail and mail-order customers) prescription growth, for the comparative periods presented, for certain of the company's U.S. primary care pharmaceutical prescription products. The estimated prescription growth amounts are based on third-party data. A significant portion of the company's domestic pharmaceutical sales is made to wholesalers. Where changes in reported net sales differ from prescription growth, this change in net sales may not reflect underlying prescriber demand.

                                                                   % Change
                                                                    in U.S.
                                                                     Total
                                                                    Prescri-
                               Worldwide Net Sales  U.S. Net Sales   ptions
                                              %                  %     vs.
                                2005  2004 Change  2005  2004 Change  2004

  Three Months Ended September 30

  Pharmaceuticals
  Cardiovascular
     Plavix                     $980  $902    9%   $833  $781     7%    12%
     Pravachol                   527   598  (12)%   297   318    (7)%  (18)%
     Avapro/Avalide              251   241    4%    147   148    (1)%   11%
     Monopril                     49    69  (29)%     1    13   (92)%  (58)%
     Coumadin                     57    65  (12)%    49    58   (16)%  (22)%
  Virology
     Sustiva                     170   157    8%    101    95     6%     6%
     Reyataz                     176   106   66%    105    75    40%    35%
     Zerit                        51    69  (26)%    24    34   (29)%  (31)%
     Videx/Videx EC               41    67  (39)%     7    27   (74)%  (72)%
  Infectious Diseases
     Cefzil                       48    54  (11)%    27    30   (10)%  (15)%
     Baraclude                     2     -    -       2     -     -    N/A
  Oncology
     Taxol                       175   243  (28)%     4     9   (56)%  N/A
     Erbitux                     107    84   27%    106    83    28 %  N/A
     Paraplatin                   42   177  (76)%     9   145   (94)%  N/A
  Affective (Psychiatric)
   Disorders
     Abilify (total revenue)     260   165    58%   214   152    41%    38%
  Metabolics
     Glucophage Franchise         43    43    -      38    39    (3)%  (46)%
  Other Pharmaceuticals
     Efferalgan                   66    61    8%      -     -     -    N/A
  Nutritionals
     Enfamil                     230   203   13%    168   137    23%   N/A
  Related Healthcare
     Ostomy                      139   135     3%    43    39    10%   N/A
     Cardiolite                  106   101     5%    95    91     4%   N/A
     Wound Therapeutics          104    99     5%    34    31    10%   N/A


                                                                      %
                                                                    Change
                                                                    in U.S.
                                                                     Total
                                                                    Prescri-
                        Worldwide Net Sales      U.S. Net Sales      ptions
                                          %                      %     vs.
                         2005    2004  Change   2005    2004  Change  2004

  Nine Months Ended September 30

  Pharmaceuticals
  Cardiovascular
     Plavix             $2,762  $2,368    17%  $2,329  $2,017    15%    14%
     Pravachol           1,672   1,925   (13)%    908     987    (8)%  (16)%
     Avapro/Avalide        705     671     5%     406     408     -     13%
     Monopril              162     206   (21)%      6      25   (76)%  (61)%
     Coumadin              156     179   (13)%    133     159   (16)%  (18)%
  Virology
     Sustiva               510     449    14%     301     261    15%     5%
     Reyataz               508     266    91%     295     206    43%    44%
     Zerit                 169     205   (18)%     76      88   (14)%  (31)%
     Videx/Videx EC        133     207   (36)%     22      81   (73)%  (62)%
  Infectious Diseases
     Cefzil                184     181     2%     107     101     6%    (9)%
     Baraclude               7       -     -        7       -     -    N/A
  Oncology
     Taxol                 566     735   (23)%     12      24   (50)%  N/A
     Erbitux               292     173    69%     290     172    69%   N/A
     Paraplatin            119     646   (82)%     23     549   (96)%  N/A
  Affective (Psychiatric)
   Disorders Abilify
   (total revenue)         688     402    71%     575     384    50%    46%
  Metabolics
     Glucophage Franchise  137     283   (52)%    121     267   (55)%  (66)%
  Other Pharmaceuticals
     Efferalgan            209     198     6%       -       -     -    N/A
  Nutritionals
     Enfamil               715     635    13%     501     439    14%   N/A
  Related Healthcare
     Ostomy                405     399     2%     115     120    (4)%   N/A
     Cardiolite            316     298     6%     282     266     6%   N/A
     Wound Therapeutics    304     280     9%      93      91     2%   N/A


                       BRISTOL-MYERS SQUIBB COMPANY
                    CONSOLIDATED STATEMENT OF EARNINGS
     FOR THE THREE AND NINE MONTHS ENDED SEPTEMBER 30, 2005 AND 2004
       (Unaudited, in millions of dollars except per share amounts)

                                         Three Months       Nine Months
                                            Ended             Ended
                                         September 30,     September 30,
                                         2005    2004      2005     2004

  Net Sales                             $4,767  $4,778  $14,188  $14,223

  Cost of products sold                  1,483   1,467    4,333    4,324
  Marketing, selling and administrative  1,286   1,199    3,737    3,626
  Advertising and product promotion        349     325    1,032      987
  Research and development                 669     615    1,971    1,823
  Acquired in-process research and
   development                               -       1        -       63
  Provision for restructuring and other
   items, net                               (5)     57        -       75
  Litigation (income)/charges, net         (26)     25       72      404
  Gain on sale of business                (569)     (3)    (569)    (316)
  Equity in net income of affiliates       (84)    (70)    (240)    (204)
  Other expense, net (a)                    38      16      168       62
                                         3,141   3,632   10,504   10,844
  Earnings from Continuing Operations
    Before Minority Interest and Income
     Taxes                               1,626   1,146    3,684    3,379
  Provision for income taxes               507     239      754      753
  Minority interest, net of taxes          155     152      437      387

  Earnings from Continuing Operations      964     755    2,493    2,239

  Discontinued Operations
    Net Earnings                             -       3       (5)      10
    Net Gain on Disposal                     -       -       13        -
                                             -       3        8       10

  Net Earnings                            $964    $758   $2,501   $2,249

  Earnings per Common Share:

  Basic:
      Earnings from Continuing
       Operations                        $0.49   $0.39    $1.28    $1.16
      Discontinued Operations
         Net Earnings                        -       -        -        -
         Net Gain on Disposal                -       -        -        -
    Net Earnings per Common Share        $0.49   $0.39    $1.28    $1.16

  Diluted:
      Earnings from Continuing
       Operations                        $0.49   $0.38    $1.27    $1.14
      Discontinued Operations
         Net Earnings                        -       -        -        -
         Net Gain on Disposal                -       -        -        -
    Net Earnings per Common Share        $0.49   $0.38    $1.27    $1.14

  Average Common Shares Outstanding:
  Basic                                  1,953   1,942    1,951    1,941
  Diluted                                1,984   1,975    1,983    1,975

  (a) Other expense/(income), net
      Interest expense                     $79     $80     $249     $219
      Interest income                      (28)    (29)     (96)     (67)
      Foreign exchange transaction
       losses/(gains)                        -     (20)      47       35
      Other, net                           (13)    (15)     (32)    (125)
                                           $38     $16     $168      $62


                                                              APPENDIX 1
                       BRISTOL-MYERS SQUIBB COMPANY
                             SPECIFIED ITEMS
          FOR THE THREE MONTHS ENDED SEPTEMBER 30, 2005 AND 2004
                   (Unaudited, in millions of dollars)

  Three months ended September 30, 2005

                                  Cost of    Gain on    Provision for
                                  products   sale of    restructuring
                                  sold       business   and other items, net

  Litigation Matters:
  Insurance recoveries               $ -        $ -          $ -

  Other:
  Gain on sale of Consumer Medicines
   businesses                          -       (569)           -
  Loss on sale of fixed assets         -          -            -
  Accelerated depreciation and asset
   impairment                         35          -            -
  Downsizing and streamlining of
   worldwide operations                -          -           (5)

                                     $35      $(569)         $(5)

  Income taxes on items above
  Increase to Net Earnings from
   Continuing Operations


  Three months ended September 30, 2004

                                     Litigation         Other         Total
                                     settlement        (income)/
                                     expense /(income)  expense, net

  Litigation Matters:
  Insurance recoveries                 $(26)              $ -         $(26)

  Other:
  Gain on sale of Consumer Medicines
   businesses                             -                 -         (569)
  Loss on sale of fixed assets            -                 1            1
  Accelerated depreciation and asset
   impairment                             -                 -           35
  Downsizing and streamlining of
   worldwide operations                   -                 -           (5)

                                       $(26)               $1         (564)

  Income taxes on items above                                           202
  Increase to Net Earnings from
   Continuing Operations                                              $(362)


  Three months ended September 30, 2004

                               Cost of     Research and  Acquired   Gain on
                               products    development   in-process sale of
                               sold                      research   business
                                                         and
                                                         development

  Litigation Matters:
  Product liability             $-              $-           $-        $-
  Anti-trust litigation          -               -            -         -
                                 -               -            -         -
  Other:
  Gain on sale of Adult
   Nutritional business          -               -            -        (3)
  Accelerated depreciation      47               1            -         -
  Downsizing and
   streamlining of
   worldwide operations          -               -            -         -
  Milestone payment              -              10            -         -
  Acordis IPR&D write-off        -               -            1         -
                               $47             $11           $1       $(3)
  Income taxes on items
   above
  Reduction to Net Earnings
   from Continuing Operations


                          Provision for    Litigation     Other      Total
                          restructuring    settlement     expense,
                          and other        expense /        net
                          items, net       (income)


  Litigation Matters:
  Product liability             $-              $-          $11      $11
  Anti-trust litigation          -              25            -       25
                                 -              25           11       36
  Other:
  Gain on sale of Adult
   Nutritional business          -               -            -       (3)
  Accelerated depreciation       -               -            -       48
  Downsizing and
   streamlining of
   worldwide operations         57               -            -       57
  Milestone payment              -               -            -       10
  Acordis IPR&D write-off        -               -            -        1
                               $57             $25          $11      149
  Income taxes on items
   above                                                             (39)
  Reduction to Net Earnings
   from Continuing Operations                                       $110



                                                              APPENDIX 1
                       BRISTOL-MYERS SQUIBB COMPANY
                             SPECIFIED ITEMS
          FOR THE NINE MONTHS ENDED SEPTEMBER 30, 2005 AND 2004
                   (Unaudited, in millions of dollars)

  Nine months ended September 30, 2005

                                       Cost of      Research and    Gain on
                                       products     development     sale of
                                       sold                         business

  Litigation Matters:
  Private litigations and governmental
   investigations                        $-              $-            $-
  ERISA liability and other matters       -               -             -
  Insurance recoveries                    -               -             -
                                          -               -             -
  Other:
  Gain on sale of equity investment       -               -             -
  Loss on sale of fixed assets            -               -             -
  Accelerated depreciation and asset
   impairment                            69               2             -
  Gain on sale of Consumer Medicines
   businesses                             -               -          (569)
  Upfront and milestone payments          -              35             -
  Debt retirement costs                   -               -             -
                                        $69             $37         $(569)
  Income taxes on items above
  Adjustment to taxes on repatriation
   of foreign earnings
  Increase to Net Earnings from
   Continuing Operations

  Nine months ended September 30, 2004


                                     Litigation         Other        Total
                                     settlement        (income)/
                                     expense /(income)  expense, net

  Litigation Matters:
  Private litigations and governmental
   investigations                     $373               $-          $373
  ERISA liability and other matters     20                -            20
  Insurance recoveries                (321)               -          (321)
                                        72                -            72
  Other:
  Gain on sale of equity investment      -              (27)          (27)
  Loss on sale of fixed assets           -               18            18
  Accelerated depreciation and asset
   impairment                            -                -            71
  Gain on sale of Consumer Medicines
   businesses                            -                -          (569)
  Upfront and milestone payments         -                -            35
  Debt retirement costs                  -               69            69
                                       $72              $60          (331)
  Income taxes on items above                                         178
  Adjustment to taxes on repatriation
   of foreign earnings                                               (135)
  Increase to Net Earnings from
   Continuing Operations                                            $(288)


  Nine months ended September 30, 2004

                         Cost of        Research and   Acquired      Gain on
                         products sold   development   in-process    sale of
                                                       research and business
                                                       development

  Litigation Matters:
  Private litigation and
   governmental
  investigations               $-            $-            $-          $-
  Product liability            75             -             -           -
  Pharmaceutical pricing and
   sales litigation             -             -             -           -
  Commercial litigation        26             -             -           -
  Anti-trust litigation         -             -             -           -
  Product liability
   insurance recovery         (25)            -             -           -
                               76             -             -           -
  Other:
  Gain on sale of Adult
   Nutritional business         -             -             -        (316)
  Accelerated depreciation     70             1             -           -
  Downsizing and
   streamlining of
   worldwide operations         1             -             -          -
  Milestone payments            -            40             -          -
  Acordis IPR&D write-off       -             -            63          -
                             $147           $41           $63      $(316)
  Income taxes on items above
  Reduction to Net Earnings
   from Continuing Operations

                         Provision for   Litigation      Other        Total
                          restructuring   settlement    expense, net
                           and other       expense /
                           items, net      (income)



  Litigation Matters:
  Private litigation and
   governmental
  investigations                 -           $320          $-         $320
  Product liability              -              -          11           86
  Pharmaceutical pricing and
   sales litigation              -             34           -           34
  Commercial litigation          -              -           -           26
  Anti-trust litigation          -             50           -           50
  Product liability
   insurance recovery            -              -           -          (25)
                                 -            404          11          491
  Other:
  Gain on sale of Adult
   Nutritional business          -              -           -         (316)
  Accelerated depreciation       -              -           4           75
  Downsizing and
   streamlining of
   worldwide operations         75              -           -           76
  Milestone payments             -              -           -           40
  Acordis IPR&D write-off        -              -           -           63
                               $75           $404         $15          429
  Income taxes on items above                                          (94)
  Reduction to Net Earnings
   from Continuing Operations                                          $335
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